1650599-68-0
Chemical Structure
IMAB027
Synonym(s): ASP1650
- CAS No.: 1650599-68-0
- Formula:N/A
- Molecular Weight:(144.42 kDa)
IUPAC Name: 2,4,7-trichloro-5-fluoroquinazoline
SMILES: [IMAB027]
Biological Activity: IMAB027 (ASP1650) is a specific anti-CLDN6 mAb, while CLDN6 (Claudin 6) is a tight junction membrane protein, aberrantly expressed in various human cancer types, ovarian cancers particularly. IMAB 027 shows anti-tumor activity, and induces apoptosis in CLDN6+ ovarian and testicular cancer cell lines[1].
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IMAB027 | 99.24% | IMAB027 (ASP1650) is a specific anti-CLDN6 mAb, while CLDN6 (Claudin 6) is a tight junction membrane protein, aberrantly expressed in various human cancer types, ovarian cancers particularly. IMAB 027 shows anti-tumor activity, and induces apoptosis in CLDN6+ ovarian and testicular cancer cell lines. | ||||||||||||||||||||
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Keywords