17303-67-2
Chemical Structure
Goniothalamin
Synonym(s): GTN; (R)-(+)-Goniothalamin
- CAS No.: 17303-67-2
- Formula:C13H12O2
- Molecular Weight:200.23
IUPAC Name: (R,E)-6-styryl-5,6-dihydro-2H-pyran-2-one
InChIKey: RLGHFVLWYYVMQZ-BZYZDCJZSA-N
SMILES: O=C1C=CC[C@H](/C=C/C2=CC=CC=C2)O1
Biological Activity: Goniothalamin (GTN) is a styryl lactone. Goniothalamin exhibits insecticidal, anti-tumor and antibacterial activities. Goniothalamin induces cell cycle arrest and apoptosis in tumor cells. Goniothalamin acts as a larvicide against Culex quinquefasciatus larvae and as a cytotoxin against brine shrimp larvae. Goniothalamin functions as an antibacterial agent against Gram-positive and Gram-negative bacteria, and also acts as an antifungal agent against pathogens including Candida albicans, Trichophyton rubrum and Trichophyton mentagrophytes. Goniothalamin is applicable to research related to breast cancer, lymphatic filariasis, bacterial infections and fungal infections[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Goniothalamin | 98.0% | Goniothalamin (GTN) is a styryl lactone. Goniothalamin exhibits insecticidal, anti-tumor and antibacterial activities. Goniothalamin induces cell cycle arrest and apoptosis in tumor cells. Goniothalamin acts as a larvicide against Culex quinquefasciatus larvae and as a cytotoxin against brine shrimp larvae. Goniothalamin functions as an antibacterial agent against Gram-positive and Gram-negative bacteria, and also acts as an antifungal agent against pathogens including Candida albicans, Trichophyton rubrum and Trichophyton mentagrophytes. Goniothalamin is applicable to research related to breast cancer, lymphatic filariasis, bacterial infections and fungal infections. | ||||||||||||||||||||
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- [1]. Chen WY, et al. Goniothalamin induces cell cycle-specific apoptosis by modulating the redox status in MDA-MB-231 cells. Eur J Pharmacol. 2005;522(1-3):20-29. [Content Brief]
- [2]. Mosaddik MA, et al. Cytotoxicity and antimicrobial activity of goniothalamin isolated from Bryonopsis laciniosa. Phytother Res. 2003;17(10):1155-1157. [Content Brief]
- [3]. Kabir K E, et al. Goniothalamin–a potent mosquito larvicide from Bryonopsis laciniosa L. Journal of Applied Entomology, 2003, 127(2): 112-115.
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