173964-49-3
Chemical Structure
NDH-1 inhibitor-1
- CAS No.: 173964-49-3
- Formula:C20H19NO3
- Molecular Weight:321.37
IUPAC Name: (3-fluoro-1-(methylsulfonyl)pyrrolidin-3-yl)methanol
InChIKey: UBQYRPXGIQUWQD-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C2C=CC=CC2=C1)NCC3=CC=C(OC)C(OC)=C3
Biological Activity: NDH-1 inhibitor-1 is a NADH-ubiquinone oxidoreductase (NDH-1) inhibitor with a pIC50 of 5.40 in potato tuber mitochondria and a pIC50 of 6.15 in Escherichia coli cell membranes. NDH-1 inhibitor-1 acts on the ubiquinone catalytic site to inhibit enzyme activity. NDH-1 inhibitor-1 can be used to study pathogenic microbial infections or mitochondrial diseases[1].
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NDH-1 inhibitor-1 | 99.88% | NDH-1 inhibitor-1 is a NADH-ubiquinone oxidoreductase (NDH-1) inhibitor with a pIC50 of 5.40 in potato tuber mitochondria and a pIC50 of 6.15 in Escherichia coli cell membranes. NDH-1 inhibitor-1 acts on the ubiquinone catalytic site to inhibit enzyme activity. NDH-1 inhibitor-1 can be used to study pathogenic microbial infections or mitochondrial diseases. | ||||||||||||||||||||
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Keywords
