174423-37-1
174423-37-1
Chemical Structure
Argyrin A
- CAS No.: 174423-37-1
- Formula:C40H44N10O8S
- Molecular Weight:824.90
InChIKey: MXGWDBFUMHUPTG-SKZNYKRCSA-N
SMILES: COC1=C2C(C[C@@H]3NC([C@@H](NC(C4=CSC([C@H](NC(CN(C(C(NC([C@H](NC(CNC3=O)=O)C)=O)=C)=O)C)=O)C)=N4)=O)CC5=CNC6=CC=CC=C56)=O)=CNC2=CC=C1
Biological Activity: Argyrin A, a cyclical peptide, is a potent antitumoral agent. Argyrin A exerts its effects through a potent inhibition of the proteasome. Argyrin A leads to increased endogenous p27kip1 levels by preventing protein turnover[1].
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Argyrin A | Argyrin A, a cyclical peptide, is a potent antitumoral agent. Argyrin A exerts its effects through a potent inhibition of the proteasome. Argyrin A leads to increased endogenous p27kip1 levels by preventing protein turnover. | |||||||||||||||||||||
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References
Keywords
