1807518-67-7
1807518-67-7
Chemical Structure
Bromoacetamido-PEG4-acid
- CAS No.: 1807518-67-7
- Formula:C13H24BrNO7
- Molecular Weight:386.24
IUPAC Name: 1-bromo-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oic acid
InChIKey: LMFYGPXSVUULRZ-UHFFFAOYSA-N
SMILES: O=C(O)CCOCCOCCOCCOCCNC(CBr)=O
Biological Activity: Bromoacetamido-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromoacetamido-PEG4-acid is also a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Bromoacetamido-PEG4-acid | 96.82% | Bromoacetamido-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Bromoacetamido-PEG4-acid is also a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | ||||||||||||||||||||
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References
- [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. [Content Brief]
- [2]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. [Content Brief]
Keywords
