1820874-51-8
1820874-51-8
Chemical Structure
MMV674850
- CAS No.: 1820874-51-8
- Formula:C23H20N2O4S2
- Molecular Weight:452.55
IUPAC Name: 5-(3-(cyclopropylsulfonyl)phenyl)-3-(4-(methylsulfonyl)phenyl)pyrazolo[1,5-a]pyridine
InChIKey: BQDDSWFSIPPWHN-UHFFFAOYSA-N
SMILES: CS(C(C=C1)=CC=C1C(C=N2)=C(N2C=C3)C=C3C4=CC(S(C5CC5)(=O)=O)=CC=C4)(=O)=O
Biological Activity: MMV674850 is potent against asexual stage parasites at 2.7 and 4.5 nM and preferentially targets early-stage gametocytes (early-stage gametocyte: IC50 4.5 ± 3.6 nM; late-stage gametocyte: IC50 28.7 ± 0.2 nM).
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MMV674850 | MMV674850 is potent against asexual stage parasites at 2.7 and 4.5 nM and preferentially targets early-stage gametocytes (early-stage gametocyte: IC50 4.5 ± 3.6 nM; late-stage gametocyte: IC50 28.7 ± 0.2 nM). | |||||||||||||||||||||
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Keywords
