182495-82-5
Chemical Structure
N4-Benzoyl-2’-deoxy-5’-O-DMTr-2’-fluoro- 5-methylcytidine
- CAS No.: 182495-82-5
- Formula:C38H36FN3O7
- Molecular Weight:665.71
IUPAC Name: N-(1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide
InChIKey: CWIJQSZZNFLZTM-DHKUXYTCSA-N
SMILES: O[C@H]1[C@@H](F)[C@H](N2C(N=C(NC(C3=CC=CC=C3)=O)C(C)=C2)=O)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6
Biological Activity: N4-Benzoyl-2’-deoxy-5’-O-DMTr-2’-fluoro- 5-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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N4-Benzoyl-2’-deoxy-5’-O-DMTr-2’-fluoro- 5-methylcytidine | N4-Benzoyl-2’-deoxy-5’-O-DMTr-2’-fluoro- 5-methylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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