1825302-42-8
Chemical Structure
H3B-8800
- CAS No.: 1825302-42-8
- Formula:C31H45N3O6
- Molecular Weight:555.71
IUPAC Name: (2S,3S,6S,7R,10R,E)-7,10-dihydroxy-3,7-dimethyl-12-oxo-2-((R,2E,4E)-6-(pyridin-2-yl)hepta-2,4-dien-2-yl)oxacyclododec-4-en-6-yl 4-methylpiperazine-1-carboxylate
InChIKey: YOIQWBAHJZGRFW-WVRLKXNASA-N
SMILES: O=C(N1CCN(C)CC1)O[C@H]([C@](C)(O)CC[C@@H](O)C2)/C=C/[C@H](C)[C@H](OC2=O)/C(C)=C/C=C/[C@@H](C)C3=NC=CC=C3
Biological Activity: H3B-8800 is a potent and orally active SF3B splicing modulator. H3B-8800 direct interaction with the SF3b complex and shows anti-cancer activity. H3B-8800 has the potential for the research of acute myeloid leukemia (AML) with SF3B1 mutant[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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H3B-8800 | 98.85% | H3B-8800 is a potent and orally active SF3B splicing modulator. H3B-8800 direct interaction with the SF3b complex and shows anti-cancer activity. H3B-8800 has the potential for the research of acute myeloid leukemia (AML) with SF3B1 mutant. | ||||||||||||||||||||
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Keywords