1825302-42-8

H3B-8800 Chemical Structure
1825302-42-8

Chemical Structure

H3B-8800

  • CAS No.: 1825302-42-8
  • Formula:C31H45N3O6
  • Molecular Weight:555.71

IUPAC Name: (2S,3S,6S,7R,10R,E)-7,10-dihydroxy-3,7-dimethyl-12-oxo-2-((R,2E,4E)-6-(pyridin-2-yl)hepta-2,4-dien-2-yl)oxacyclododec-4-en-6-yl 4-methylpiperazine-1-carboxylate

InChIKey: YOIQWBAHJZGRFW-WVRLKXNASA-N

SMILES: O=C(N1CCN(C)CC1)O[C@H]([C@](C)(O)CC[C@@H](O)C2)/C=C/[C@H](C)[C@H](OC2=O)/C(C)=C/C=C/[C@@H](C)C3=NC=CC=C3

Biological Activity: H3B-8800 is a potent and orally active SF3B splicing modulator. H3B-8800 direct interaction with the SF3b complex and shows anti-cancer activity. H3B-8800 has the potential for the research of acute myeloid leukemia (AML) with SF3B1 mutant[1].

Cat. No. Product Name Purity Description Pricing
HY-111517
H3B-8800 98.85% H3B-8800 is a potent and orally active SF3B splicing modulator. H3B-8800 direct interaction with the SF3b complex and shows anti-cancer activity. H3B-8800 has the potential for the research of acute myeloid leukemia (AML) with SF3B1 mutant.
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