1839583-42-4
1839583-42-4
Chemical Structure
ASP8302
- CAS No.: 1839583-42-4
- Formula:C26H32ClN7O3S2
- Molecular Weight:590.16
InChIKey: QEVOTPLHYBIHKJ-SJORKVTESA-N
SMILES: O=C(C1=NC=C(N2C[C@@H](N(CC2)CCC(O)=O)C)N=C1)NC(S3)=NC(C4=CC(Cl)=CS4)=C3CN5[C@@H](CCC5)C
Biological Activity: ASP8302 is a positive and allosteric muscarinic M3 receptor modulator. ASP8302 improves voiding efficiency and reduced residual urine volume in two voiding dysfunction models. ASP8302 can be used for research of underactive bladder[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ASP8302 | 98.95% | ASP8302 is a positive and allosteric muscarinic M3 receptor modulator. ASP8302 improves voiding efficiency and reduced residual urine volume in two voiding dysfunction models. ASP8302 can be used for research of underactive bladder. | ||||||||||||||||||||
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References
- [1]. Okimoto R, et al. Potentiation of Muscarinic M3 Receptor Activation through a New Allosteric Site with a Novel Positive Allosteric Modulator ASP8302. J Pharmacol Exp Ther. 2021 Oct;379(1):64-73. [Content Brief]
- [2]. Okimoto R, et al. Muscarinic M3 positive allosteric modulator ASP8302 enhances bladder contraction and improves voiding dysfunction in rats. Low Urin Tract Symptoms. 2022 Jul;14(4):289-300. [Content Brief]
Keywords
