18472-51-0
Chemical Structure
Chlorhexidine digluconate (20% in water)
- CAS No.: 18472-51-0
- Formula:C34H54Cl2N10O14
- Molecular Weight:897.76
InChIKey: YZIYKJHYYHPJIB-UUPCJSQJSA-N
SMILES: N=C(NC(NCCCCCCNC(NC(NC1=CC=C(Cl)C=C1)=N)=N)=N)NC2=CC=C(Cl)C=C2.O[C@H]([C@@H](O)C(O)=O)[C@H](O)[C@H](O)CO.O[C@H]([C@@H](O)C(O)=O)[C@H](O)[C@H](O)CO
Biological Activity:
Chlorhexidine digluconate (20% in water) is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine digluconate (20% in water) binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine digluconate (20% in water) has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine digluconate (20% in water) can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis)[1][2][3].
The product specifications provided below refer solely to the active content of Chlorhexidine digluconate.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Chlorhexidine digluconate (20% in water) | 98.88% | Chlorhexidine digluconate (20% in water) is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine digluconate (20% in water) binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine digluconate (20% in water) has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine digluconate (20% in water) can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis). The product specifications provided below refer solely to the active content of Chlorhexidine digluconate. |
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Similarity Score 0.75
HY-W013699RChlorhexidine diacetate (Standard) -
Similarity Score 0.72
HY-B1248RChlorhexidine (Standard) -
Similarity Score 0.71
HY-B1145Chlorhexidine dihydrochloride -
Similarity Score 0.57
HY-W587449Chlorhexidine impurity 1 -
Similarity Score 0.55
HY-125654COlanexidine (gluconate) -
Similarity Score 0.54
HY-U00120Picloxydine -
Similarity Score 0.50
HY-B1145SChlorhexidine-d8 dihydrochloride -
Similarity Score 0.50
HY-W738281Chlorhexidine-d8 -
Similarity Score 0.45
HY-B1476RNSC 42196 (Standard) -
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References
- [1]. Faria G, et al. Evaluation of chlorhexidine toxicity injected in the paw of mice and added to cultured l929 fibroblasts. J Endod. 2007 Jun;33(6):715-22. [Content Brief]
- [2]. Sanchez IR, et al. Chlorhexidine diacetate and povidone-iodine cytotoxicity to canine embryonic fibroblasts and Staphylococcus aureus. Vet Surg. 1988;17(4):182-185. [Content Brief]
- [3]. Zhang J, et al. Pulmonary Toxicity Assessment after a Single Intratracheal Inhalation of Chlorhexidine Aerosol in Mice. Toxics. 2023 Nov 7;11(11):910. [Content Brief]
