1848223-48-2
1848223-48-2
Chemical Structure
4′,5′-Didehydro-5′-deoxy-2′-O-methyluridine
- CAS No.: 1848223-48-2
- Formula:C10H12N2O5
- Molecular Weight:240.21
IUPAC Name: 1-((2R,3R,4S)-4-hydroxy-3-methoxy-5-methylenetetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: AYTOADFYFHPUBK-IWSPIJDZSA-N
SMILES: C=C1[C@@H](O)[C@@H](OC)[C@H](N2C(NC(C=C2)=O)=O)O1
Biological Activity: 4′,5′-Didehydro-5′-deoxy-2′-O-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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4′,5′-Didehydro-5′-deoxy-2′-O-methyluridine | 4′,5′-Didehydro-5′-deoxy-2′-O-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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