185418-37-5
Chemical Structure
PSF-IN-2
- CAS No.: 185418-37-5
- Formula:C18H16O5
- Molecular Weight:312.32
InChIKey: IXWVVHIJMCHVBS-UHFFFAOYSA-N
SMILES: O=C1OC2=C(C(C3=CC=C(OC)C=C3)=C1)C=CC(OC)=C2OC
Biological Activity: PSF-IN-2 (Compound (C)-30) is a PSF inhibitor with an IC50 value of 0.005 pM. PSF-IN-2 exhibits anti-cancer activity, and its IC50 value for inhibiting the proliferation of 22Rv1 cells is 0.5 μM. PSF-IN-2 activates the p53 signaling pathway by inhibiting the binding of PSF to RNA, inducing the expression of related genes, promoting apoptosis, and inhibiting the cell cycle. PSF-IN-2 can be used in cancer research[1].
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PSF-IN-2 | 99.85% | PSF-IN-2 (Compound (C)-30) is a PSF inhibitor with an IC50 value of 0.005 pM. PSF-IN-2 exhibits anti-cancer activity, and its IC50 value for inhibiting the proliferation of 22Rv1 cells is 0.5 μM. PSF-IN-2 activates the p53 signaling pathway by inhibiting the binding of PSF to RNA, inducing the expression of related genes, promoting apoptosis, and inhibiting the cell cycle. PSF-IN-2 can be used in cancer research. | ||||||||||||||||||||
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Keywords
