189950-66-1
189950-66-1
Chemical Structure
Ac-DEVD-pNA
- CAS No.: 189950-66-1
- Formula:C26H34N6O13
- Molecular Weight:638.58
IUPAC Name: (2S,5S,8S,11S)-8-(2-carboxyethyl)-11-(carboxymethyl)-5-isopropyl-2-(2-((4-nitrophenyl)amino)-2-oxoethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecanoic acid
InChIKey: DAOMBBSDYYRHPX-ORGXJRBJSA-N
SMILES: O=C(N[C@@H](C(C)C)C(N[C@H](C(O)=O)CC(NC1=CC=C([N+]([O-])=O)C=C1)=O)=O)[C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC(O)=O)=O
Biological Activity: Ac-DEVD-pNA is a ligand for caspase-3/-7 and related cysteine proteases[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ac-DEVD-pNA | 99.70% | Ac-DEVD-pNA is a ligand for caspase-3/-7 and related cysteine proteases. | ||||||||||||||||||||
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References
- [1]. Talanian RV, et al. Substrate specificities of caspase family proteases. J Biol Chem. 1997 Apr 11;272(15):9677-82. [Content Brief]
- [2]. Peterson QP, et al. Preparation of the caspase-3/7 substrate Ac-DEVD-pNA by solution-phase peptide synthesis. Nat Protoc. 2010 Feb;5(2):294-302. [Content Brief]
Keywords
