1939104-08-1

JH-IX-179 Chemical Structure
1939104-08-1

Chemical Structure

JH-IX-179

  • CAS No.: 1939104-08-1
  • Formula:C26H24N6O
  • Molecular Weight:436.51

IUPAC Name: 3-(1-(3-(dimethylamino)propyl)-1H-pyrazol-4-yl)-7-(1H-pyrazol-4-yl)indeno[1,2-b]indol-10(5H)-one

InChIKey: JRJKATLTRNXYCE-UHFFFAOYSA-N

SMILES: O=C1C2=C(C(N3)=C1C4=C3C=C(C5=CNN=C5)C=C4)C=C(C6=CN(CCCN(C)C)N=C6)C=C2

Biological Activity: JH-IX-179 is an FLT3 inhibitor (IC50 = 4 nM (FLT3-ITD), 10 nM (FLT3-D835Y)). JH-IX-179 inhibits G1 phase arrest and induces apoptosis in FLT3-ITD-expressing cells. JH-IX-179 can be used in acute myeloid leukemia (AML) research[1].

Cat. No. Product Name Purity Description Pricing
HY-125008 		JH-IX-179 JH-IX-179 is an FLT3 inhibitor (IC50 = 4 nM (FLT3-ITD), 10 nM (FLT3-D835Y)). JH-IX-179 inhibits G1 phase arrest and induces apoptosis in FLT3-ITD-expressing cells. JH-IX-179 can be used in acute myeloid leukemia (AML) research.
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