194034-84-9
194034-84-9
Chemical Structure
5’-Deoxy-5’-iodo-2’-O-methyluridine
- CAS No.: 194034-84-9
- Formula:C9H11IN2O5
- Molecular Weight:354.10
IUPAC Name: 1-((2R,3R,4S,5R)-4-hydroxy-5-iodo-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: JMEJDLIBFAVBNR-FKSUSPILSA-N
SMILES: O[C@H]1[C@@H](OC)[C@H](N(C(N2)=O)C=CC2=O)O[C@@H]1I
Biological Activity: 5’-Deoxy-5’-iodo-2’-O-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5’-Deoxy-5’-iodo-2’-O-methyluridine | 5’-Deoxy-5’-iodo-2’-O-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
Keywords
