1972617-87-0
Chemical Structure
GSK3186899
Synonym(s): DDD-853651
- CAS No.: 1972617-87-0
- Formula:C19H28F3N7O3S
- Molecular Weight:491.53
IUPAC Name: 3,3,3-trifluoro-N-((1S,4r)-4-((3-((S)-2-methylmorpholino)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino)cyclohexyl)propane-1-sulfonamide
InChIKey: RQWCISVRFNZHMJ-IHRRRGAJSA-N
SMILES: O=S(CCC(F)(F)F)(N[C@H]1CC[C@H](NC2=NC=C3C(NN=C3N4C[C@H](C)OCC4)=N2)CC1)=O
Biological Activity: GSK3186899 (DDD-853651) is an inhibitor of cdc-2-related kinase 12 (CRK12), with an EC50 of 1.4 μM for L. donovani in an intra-macrophage assay.
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GSK3186899 | 98.96% | GSK3186899 (DDD-853651) is an inhibitor of cdc-2-related kinase 12 (CRK12), with an EC50 of 1.4 μM for L. donovani in an intra-macrophage assay. | ||||||||||||||||||||
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Keywords