20168-99-4
Chemical Structure
Cinmetacin
- CAS No.: 20168-99-4
- Formula:C21H19NO4
- Molecular Weight:349.38
IUPAC Name: 2-(1-cinnamoyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid
InChIKey: NKPPORKKCMYYTO-DHZHZOJOSA-N
SMILES: O=C(O)CC1=C(C)N(C(/C=C/C2=CC=CC=C2)=O)C3=C1C=C(OC)C=C3
Biological Activity: Cinmetacin is an orally active and selective anti-inflammatory agent targeting cyclooxygenase (COX). Cinmetacin is promising for research of inflammatory diseases (e.g., arthritis)[1][2].
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Cinmetacin | Cinmetacin is an orally active and selective anti-inflammatory agent targeting cyclooxygenase (COX). Cinmetacin is promising for research of inflammatory diseases (e.g., arthritis). | |||||||||||||||||||||
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- [1]. Kim Y B, et al. The crystal structure of cinmetacin (C21 H19 NO4), a non-steroidal antiinflammatory agent[J]. Archives of Pharmacal Research, 1989, 12(1): 52-57.
- [2]. Myung S W, et al. Gas chromatographic—electron-impact chemical ionization mass spectrometric identification of cinmetacin and its metabolites in human urine[J]. Journal of Chromatography B: Biomedical Sciences and Applications, 1994, 660(1): 75-84. [Content Brief]
Keywords