2026635-66-3
2026635-66-3
Chemical Structure
GNE 5729
- CAS No.: 2026635-66-3
- Formula:C17H10Cl2F3N5O
- Molecular Weight:428.20
IUPAC Name: (1R,2R)-2-(7-chloro-2-((5-chloro-3-(trifluoromethyl)-1H-pyrazol-1-yl)methyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-6-yl)cyclopropane-1-carbonitrile
InChIKey: GPMGDUIAVSFGGH-WCBMZHEXSA-N
SMILES: ClC1=C([C@H]2[C@H](C#N)C2)N3C(C=C1)=NC(CN4N=C(C(F)(F)F)C=C4Cl)=CC3=O
Biological Activity: GNE 5729 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 37 nM for GluN2A, 4.7 and 9.5 μM for GluN2C and GluN2D, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GNE 5729 | 99.05% | GNE 5729 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 37 nM for GluN2A, 4.7 and 9.5 μM for GluN2C and GluN2D, respectively. | ||||||||||||||||||||
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Keywords
