2054345-69-4
Chemical Structure
Azide-PEG3-L-alanine-Fmoc
- CAS No.: 2054345-69-4
- Formula:C24H28N4O7
- Molecular Weight:484.50
IUPAC Name: N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(2-(2-(2-azidoethoxy)ethoxy)ethyl)-D-serine
InChIKey: YTHKPQSMRZQREU-JOCHJYFZSA-N
SMILES: O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)N[C@@H](C(O)=O)COCCOCCOCCN=[N+]=[N-]
Biological Activity: Azide-PEG3-L-alanine-Fmoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG3-L-alanine-Fmoc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Azide-PEG3-L-alanine-Fmoc | Azide-PEG3-L-alanine-Fmoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azide-PEG3-L-alanine-Fmoc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Keywords
