2055198-04-2
Chemical Structure
PC-Biotin-PEG4-PEG3-azide
- CAS No.: 2055198-04-2
- Formula:C39H63N9O14S
- Molecular Weight:914.03
IUPAC Name: 1-(5-(3,19-dioxo-23-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-6,9,12,15-tetraoxa-2,18-diazatricosyl)-2-nitrophenyl)ethyl (2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)carbamate
InChIKey: APXHNGAQDHMBFB-OITTVKJVSA-N
SMILES: O=C(OC(C1=CC(CNC(CCOCCOCCOCCOCCNC(CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O)=O)=O)=CC=C1[N+]([O-])=O)C)NCCOCCOCCOCCN=[N+]=[N-]
Biological Activity: PC-Biotin-PEG4-PEG3-azide is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PC-Biotin-PEG4-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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PC-Biotin-PEG4-PEG3-azide | PC-Biotin-PEG4-PEG3-azide is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). PC-Biotin-PEG4-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Keywords
