2055821-33-3
2055821-33-3
Chemical Structure
ALK-IN-6
- CAS No.: 2055821-33-3
- Formula:C26H29D3ClN5O3S
- Molecular Weight:533.10
IUPAC Name: 5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-(methoxy-d3)-5-methyl-4-(piperidin-4-yl)phenyl)pyrimidine-2,4-diamine
InChIKey: BXJYIWUWXJWABE-GKOSEXJESA-N
SMILES: ClC1=CN=C(NC2=C(OC([2H])([2H])[2H])C=C(C3CCNCC3)C(C)=C2)N=C1NC4=CC=CC=C4S(=O)(C(C)C)=O
Biological Activity: ALK-IN-6 (compound 11) is an orally bioavailable inhibitor of anaplastic lymphoma kinase (ALK), with IC50 values of 71 nM, 18.72 nM and 36.81 nM for ALK wild, ALK F1196M and ALK F1174L, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
ALK-IN-6 | ALK-IN-6 (compound 11) is an orally bioavailable inhibitor of anaplastic lymphoma kinase (ALK), with IC50 values of 71 nM, 18.72 nM and 36.81 nM for ALK wild, ALK F1196M and ALK F1174L, respectively. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
