1. Protein Tyrosine Kinase/RTK
  2. ALK
  3. ALK-IN-6

ALK-IN-6 

Cat. No.: HY-128596
Handling Instructions

ALK-IN-6 (compound 11) is an orally bioavailable inhibitor of anaplastic lymphoma kinase (ALK), with IC50 values of 71 nM, 18.72 nM and 36.81 nM for ALK wild, ALK F1196M and ALK F1174L, respectively.

For research use only. We do not sell to patients.

ALK-IN-6 Chemical Structure

ALK-IN-6 Chemical Structure

CAS No. : 2055821-33-3

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Description

ALK-IN-6 (compound 11) is an orally bioavailable inhibitor of anaplastic lymphoma kinase (ALK), with IC50 values of 71 nM, 18.72 nM and 36.81 nM for ALK wild, ALK F1196M and ALK F1174L, respectively[1].

IC50 & Target

IC50: 71 nM (ALK wild), 18.72 nM (ALK F1196M), 36.81 nM (ALK F1174L)[1].

Molecular Weight

533.10

Formula

C₂₆H₂₉D₃ClN₅O₃S

CAS No.

2055821-33-3

SMILES

ClC1=CN=C(NC2=C(OC([2H])([2H])[2H])C=C(C3CCNCC3)C(C)=C2)N=C1NC4=CC=CC=C4S(=O)(C(C)C)=O

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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ALK-IN-6
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