2070014-82-1
2070014-82-1
Chemical Structure
Osimertinib dimesylate
Synonym(s): AZD-9291 dimesylate; Mereletinib dimesylate
- CAS No.: 2070014-82-1
- Formula:C30H41N7O8S2
- Molecular Weight:691.82
IUPAC Name: N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide dimethanesulfonate
InChIKey: RPUCCTLBBCSFEX-UHFFFAOYSA-N
SMILES: CS(=O)(O)=O.C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C)=O.CS(=O)(O)=O
Biological Activity: Osimertinib dimesylate (AZD-9291 dimesylate) is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R/T790M, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Osimertinib dimesylate | 99.00% | Osimertinib dimesylate (AZD-9291 dimesylate) is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R/T790M, respectively. | ||||||||||||||||||||
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Osimertinib dimesylate (Standard) | ≥98% | Osimertinib (dimesylate) (Standard) is the analytical standard of Osimertinib (dimesylate). This product is intended for research and analytical applications. Osimertinib dimesylate (AZD-9291 dimesylate) is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R/T790M, respectively. | ||||||||||||||||||||
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