2072145-77-6
2072145-77-6
Chemical Structure
2’-Deoxy-2’-fluoro-N3-(4-nitrobenzyl)-beta-D-arabinouridine
- CAS No.: 2072145-77-6
- Formula:C16H16FN3O7
- Molecular Weight:381.31
IUPAC Name: 1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3-(4-nitrobenzyl)pyrimidine-2,4(1H,3H)-dione
InChIKey: AOOYPGSHBAUMFT-FAAHXZRKSA-N
SMILES: OC[C@@H]1[C@@H](O)[C@H](F)[C@H](N(C=CC2=O)C(N2CC3=CC=C([N+]([O-])=O)C=C3)=O)O1
Biological Activity: 2’-Deoxy-2’-fluoro-N3-(4-nitrobenzyl)-beta-D-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’-Deoxy-2’-fluoro-N3-(4-nitrobenzyl)-beta-D-arabinouridine | 2’-Deoxy-2’-fluoro-N3-(4-nitrobenzyl)-beta-D-arabinouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
