2083621-90-1
2083621-90-1
Chemical Structure
MBM-17
- CAS No.: 2083621-90-1
- Formula:C28H28N6O2
- Molecular Weight:480.56
IUPAC Name: 2-(benzyloxy)-4-(7-(1-(2-(dimethylamino)ethyl)-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl)benzamide
InChIKey: RENORGCYKWQFMO-UHFFFAOYSA-N
SMILES: NC(C(C=C1)=C(OCC2=CC=CC=C2)C=C1C3=CN=C4N3C=CC(C5=CN(CCN(C)C)N=C5)=C4)=O
Biological Activity: MBM-17 is a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM. It effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis. MBM-55 shows antitumor activities, and no obvious toxicity to mice[1].
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MBM-17 | MBM-17 is a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM. It effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis. MBM-55 shows antitumor activities, and no obvious toxicity to mice. | |||||||||||||||||||||
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References
Keywords
