2107273-38-9
Chemical Structure
N-(m-PEG4)-N'-(azide-PEG4)-Cy3
- CAS No.: 2107273-38-9
- Formula:C42H62ClN5O8
- Molecular Weight:800.42
IUPAC Name: 2-((E)-3-((E)-1-(14-azido-3,6,9,12-tetraoxatetradecyl)-3,3-dimethylindolin-2-ylidene)prop-1-en-1-yl)-3,3-dimethyl-1-(2,5,8,11-tetraoxatridecan-13-yl)-3H-indol-1-ium chloride
InChIKey: YRFRBTOMOUXLRJ-UHFFFAOYSA-M
SMILES: CC1(C)C(/C=C/C=C2N(CCOCCOCCOCCOCCN=[N+]=[N-])C3=C(C=CC=C3)C/2(C)C)=[N+](CCOCCOCCOCCOC)C4=C1C=CC=C4.[Cl-]
Biological Activity: N-(m-PEG4)-N'-(azide-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(m-PEG4)-N'-(azide-PEG4)-Cy3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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N-(m-PEG4)-N'-(azide-PEG4)-Cy3 | N-(m-PEG4)-N'-(azide-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-(m-PEG4)-N'-(azide-PEG4)-Cy3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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