2107273-64-1
Chemical Structure
N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3
- CAS No.: 2107273-64-1
- Formula:C44H66ClN5O10
- Molecular Weight:860.48
IUPAC Name: 5-((2,5,8,11-tetraoxatridecan-13-yl)oxy)-2-((E)-3-((E)-5-((14-azido-3,6,9,12-tetraoxatetradecyl)oxy)-1,3,3-trimethylindolin-2-ylidene)prop-1-en-1-yl)-1,3,3-trimethyl-3H-indol-1-ium chloride
InChIKey: FHRNKBLFTPHSBL-UHFFFAOYSA-M
SMILES: CC(C1=C(N/2C)C=CC(OCCOCCOCCOCCOCCN=[N+]=[N-])=C1)(C)C2=C/C=C/C3=[N+](C)C4=C(C=C(OCCOCCOCCOCCOC)C=C4)C3(C)C.[Cl-]
Biological Activity: N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 | N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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