2130881-32-0
2130881-32-0
Chemical Structure
RTICBM-74
- CAS. Nr.: 2130881-32-0
- Formula:C19H14ClFN2O
- Molecular Weight:340.78
InChIKey: XVGAWVMMVIOVSW-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(C2=CC=C(F)C=C2)=CC=C1)NC3=CC=C(C=C3)Cl
Biological Activity: RTICBM-74 is a blood-brain barrier-permeable, selective CB1 allosteric modulator with IC50 values of 23 nM (calcium mobilization assay) and 153 nM ([35S]GTPγS assay). RTICBM-74 inhibits CB1 receptor signaling. RTICBM-74 reduces alcohol intake in rats. RTICBM-74 can be used for the research of alcohol use disorder[1].
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RTICBM-74 | RTICBM-74 is a blood-brain barrier-permeable, selective CB1 allosteric modulator with IC50 values of 23 nM (calcium mobilization assay) and 153 nM ([35S]GTPγS assay). RTICBM-74 inhibits CB1 receptor signaling. RTICBM-74 reduces alcohol intake in rats. RTICBM-74 can be used for the research of alcohol use disorder. | |||||||||||||||||||||
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References
Keywords
