2131223-64-6
Chemical Structure
YW1128
- CAS No.: 2131223-64-6
- Formula:C20H17N5O
- Molecular Weight:343.38
IUPAC Name: 5-methyl-N-(quinolin-2-yl)-1-(o-tolyl)-1H-1,2,3-triazole-4-carboxamide
InChIKey: SXZFICNOPPNYJM-UHFFFAOYSA-N
SMILES: O=C(C1=C(C)N(C2=CC=CC=C2C)N=N1)NC3=NC4=CC=CC=C4C=C3
Biological Activity: YW1128 (compound 3a) is a potent Wnt/β-Catenin inhibitor. YW1128 induces the proteasome degradation of β-catenin and subsequent inhibits the Wnt/β-catenin signaling in cells. YW1128 significantly decreases hepatic lipid accumulation. YW1128 improves glucose tolerance of high fat diet-fed mice without noticeable toxicity. YW1128 down regulates the genes involved in the glucose and fatty acid anabolism[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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YW1128 | 99.38% | YW1128 (compound 3a) is a potent Wnt/β-Catenin inhibitor. YW1128 induces the proteasome degradation of β-catenin and subsequent inhibits the Wnt/β-catenin signaling in cells. YW1128 significantly decreases hepatic lipid accumulation. YW1128 improves glucose tolerance of high fat diet-fed mice without noticeable toxicity. YW1128 down regulates the genes involved in the glucose and fatty acid anabolism. | ||||||||||||||||||||
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Keywords
