2143467-62-1
2143467-62-1
Chemical Structure
BPK-29
- CAS. Nr.: 2143467-62-1
- Formula:C26H32ClN3O3
- Molecular Weight:470.00
IUPAC Name: N-benzyl-2-chloro-N-(1-(4-morpholinobenzoyl)azepan-4-yl)acetamide
InChIKey: ZKWKNYRAPOSUDO-UHFFFAOYSA-N
SMILES: O=C(N(C1CCN(C(C2=CC=C(N3CCOCC3)C=C2)=O)CCC1)CC4=CC=CC=C4)CCl
Biological Activity: BPK-29 is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein (such RBM45 and SNW1) interactions by covalently modifying C274. BPK-29 impairs the anchorage-independent growth of KEAP1-mutant cancer cells[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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BPK-29 | 99.4% | BPK-29 is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein (such RBM45 and SNW1) interactions by covalently modifying C274. BPK-29 impairs the anchorage-independent growth of KEAP1-mutant cancer cells. | ||||||||||||||||||||
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References
Keywords
