2170137-61-6

GSK-3685032 Chemical Structure
2170137-61-6

Chemical Structure

GSK-3685032

  • CAS No.: 2170137-61-6
  • Formula:C22H24N6OS
  • Molecular Weight:420.53

IUPAC Name: 2-((6-(4-aminopiperidin-1-yl)-3,5-dicyano-4-ethylpyridin-2-yl)thio)-2-phenylacetamide

InChIKey: KNKHRZYILDZLRE-UHFFFAOYSA-N

SMILES: N#CC1=C(SC(C2=CC=CC=C2)C(N)=O)N=C(N3CCC(CC3)N)C(C#N)=C1CC

Biological Activity: GSK-3685032 is a non-time-dependent, noncovalently, first-in-class reversible DNMT1-selective inhibitor, with an IC50 of 0.036 μM. GSK-3685032 induces robust loss of DNA methylation, transcriptional activation, and cancer cell growth inhibition[1].

Cat. No. 상품명 Purity 제품 설명 Pricing
HY-139664
GSK-3685032 99.41% GSK-3685032 is a non-time-dependent, noncovalently, first-in-class reversible DNMT1-selective inhibitor, with an IC50 of 0.036 μM. GSK-3685032 induces robust loss of DNA methylation, transcriptional activation, and cancer cell growth inhibition.
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