217180-81-9

Azido-PEG5-CH2CO2H Chemical Structure
217180-81-9

Chemical Structure

Azido-PEG5-CH2CO2H

  • CAS No.: 217180-81-9
  • Formula:C12H23N3O7
  • Molecular Weight:321.33

IUPAC Name: 17-azido-3,6,9,12,15-pentaoxaheptadecanoic acid

InChIKey: CEACGPKHPWXRQF-UHFFFAOYSA-N

SMILES: O=C(O)COCCOCCOCCOCCOCCN=[N+]=[N-]

Biological Activity: Azido-PEG5-CH2CO2H is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-CH2CO2H is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG5-CH2CO2H is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No. Product Name Purity Description Pricing
HY-130194 		Azido-PEG5-CH2CO2H 98.88% Azido-PEG5-CH2CO2H is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-CH2CO2H is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG5-CH2CO2H is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

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