2183440-70-0
Chemical Structure
N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid
- CAS No.: 2183440-70-0
- Formula:C24H47N5O11
- Molecular Weight:581.66
IUPAC Name: 12-(3-(2-(2-aminoethoxy)ethoxy)propanoyl)-1-azido-3,6,9,15,18,21-hexaoxa-12-azatetracosan-24-oic acid
InChIKey: FZLMDRGRFLPQRO-UHFFFAOYSA-N
SMILES: O=C(O)CCOCCOCCOCCN(C(CCOCCOCCN)=O)CCOCCOCCOCCN=[N+]=[N-]
Biological Activity: N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid | 97.0% | N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | ||||||||||||||||||||
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