2183440-74-4
Chemical Structure
N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid
- CAS No.: 2183440-74-4
- Formula:C29H55N5O13
- Molecular Weight:681.77
IUPAC Name: 15-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)-2,2-dimethyl-4,14-dioxo-3,8,11,18,21,24-hexaoxa-5,15-diazaheptacosan-27-oic acid
InChIKey: KGAMPVINRLXGCH-UHFFFAOYSA-N
SMILES: O=C(OC(C)(C)C)NCCOCCOCCC(N(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCC(O)=O)=O
Biological Activity: N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid | 98.07% | N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | ||||||||||||||||||||
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