2231666-57-0
2231666-57-0
Chemical Structure
(1R,9S)-Exatecan
Synonym(s): (1R,9S)-DX-8951
- CAS No.: 2231666-57-0
- Formula:C24H22FN3O4
- Molecular Weight:435.45
InChIKey: ZVYVPGLRVWUPMP-GYCJOSAFSA-N
SMILES: N[C@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C(CC1)=C62
Biological Activity: (1R,9S)-Exatecan (DX8951) is the (1R,9S) stereoisomer of Exatecan (HY-13631). Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research[1].
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(1R,9S)-Exatecan | (1R,9S)-Exatecan (DX8951) is the (1R,9S) stereoisomer of Exatecan (HY-13631). Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research. | |||||||||||||||||||||
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References
Keywords
