2243566-43-8
Chemical Structure
Azido-PEG3-amide-C3-triethoxysilane
- CAS No.: 2243566-43-8
- Formula:C18H38N4O7Si
- Molecular Weight:450.60
IUPAC Name: 3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)-N-(3-(triethoxysilyl)propyl)propanamide
InChIKey: BCFMWIGPFZSBNT-UHFFFAOYSA-N
SMILES: O=C(NCCC[Si](OCC)(OCC)OCC)CCOCCOCCOCCN=[N+]=[N-]
Biological Activity: Azido-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG3-amide-C3-triethoxysilane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Azido-PEG3-amide-C3-triethoxysilane | Azido-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG3-amide-C3-triethoxysilane is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Keywords