2245820-70-4
2245820-70-4
Chemical Structure
RIPK2-IN-1
- CAS No.: 2245820-70-4
- Formula:C23H27N5O3S
- Molecular Weight:453.56
IUPAC Name: N-(3-(2-amino-5-(4-(piperazin-1-yl)phenyl)pyridin-3-yl)-5-methoxyphenyl)methanesulfonamide
InChIKey: WTNLXMJMLHJDKF-UHFFFAOYSA-N
SMILES: COC1=CC(C2=C(N=CC(C3=CC=C(C=C3)N4CCNCC4)=C2)N)=CC(NS(C)(=O)=O)=C1
Biological Activity: RIPK2-IN-1 (compound 18f) is a potent RIPK2 inhibitor with an IC50 of 51 nM. RIPK2-IN-1 inhibits ALK2 with an IC50 of 5 nM. RIPK2-IN-1 has an IC50 of 390 nM on RIPK2/NOD2 in cell assay[1].
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RIPK2-IN-1 | RIPK2-IN-1 (compound 18f) is a potent RIPK2 inhibitor with an IC50 of 51 nM. RIPK2-IN-1 inhibits ALK2 with an IC50 of 5 nM. RIPK2-IN-1 has an IC50 of 390 nM on RIPK2/NOD2 in cell assay. | |||||||||||||||||||||
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References
Keywords
