2247911-68-6
Chemical Structure
Lipoxygenin
- CAS No.: 2247911-68-6
- Formula:C24H22N2O4
- Molecular Weight:402.44
IUPAC Name: naphthalen-2-yl(2',4,6-trimethoxy-[3,3'-bipyridin]-5-yl)methanol
InChIKey: OSVNGDATIGOCLA-UHFFFAOYSA-N
SMILES: OC(C1=C(OC)N=CC(C2=CC=CN=C2OC)=C1OC)C3=CC4=C(C=CC=C4)C=C3
Biological Activity: Lipoxygenin is a non-redox 5-lipoxygenase (5-LO) inhibitor with an IC50 of 5 μM. Lipoxygenin modulates the β-catenin-5-LO complex, inducing a decrease in β-catenin and 5-LO levels in the nucleus[1].
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Lipoxygenin | Lipoxygenin is a non-redox 5-lipoxygenase (5-LO) inhibitor with an IC50 of 5 μM. Lipoxygenin modulates the β-catenin-5-LO complex, inducing a decrease in β-catenin and 5-LO levels in the nucleus. | |||||||||||||||||||||
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Keywords