2253745-70-7
2253745-70-7
Chemical Structure
mPGES1-IN-5
- CAS No.: 2253745-70-7
- Formula:C27H27N3O
- Molecular Weight:409.52
IUPAC Name: 4-(4-(benzyloxy)phenyl)-5-butyl-6-phenylpyrimidin-2-amine
InChIKey: NTDRTEHIZUWZQO-UHFFFAOYSA-N
SMILES: NC1=NC(C2=CC=C(OCC3=CC=CC=C3)C=C2)=C(CCCC)C(C4=CC=CC=C4)=N1
Biological Activity: mPGES1-IN-5 (compound 18) is a polysubstituted pyrimidine compound and a submicromolar PGE2 production inhibitor. It exerts its anti-inflammatory effect mainly by inhibiting mPGES-1 and has a significant inhibitory effect on the acute inflammation model in vivo.
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mPGES1-IN-5 | mPGES1-IN-5 (compound 18) is a polysubstituted pyrimidine compound and a submicromolar PGE2 production inhibitor. It exerts its anti-inflammatory effect mainly by inhibiting mPGES-1 and has a significant inhibitory effect on the acute inflammation model in vivo. | |||||||||||||||||||||
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Keywords
