2253745-78-5
Chemical Structure
mPGES1-IN-4
- CAS No.: 2253745-78-5
- Formula:C27H25F2N3O
- Molecular Weight:445.50
IUPAC Name: 4-(4-(benzyloxy)-2,3-difluorophenyl)-5-butyl-6-phenylpyrimidin-2-amine
InChIKey: DJHKSTXSNQFUFJ-UHFFFAOYSA-N
SMILES: FC1=C(OCC2=CC=CC=C2)C=CC(C3=C(CCCC)C(C4=CC=CC=C4)=NC(N)=N3)=C1F
Biological Activity: mPGES1-IN-4 (compound 32) is a polysubstituted pyrimidine compound and a submicromolar PGE2 production inhibitor. It exerts its anti-inflammatory effect mainly by inhibiting mPGES-1 and has a significant inhibitory effect on the acute inflammation model in vivo.
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mPGES1-IN-4 | mPGES1-IN-4 (compound 32) is a polysubstituted pyrimidine compound and a submicromolar PGE2 production inhibitor. It exerts its anti-inflammatory effect mainly by inhibiting mPGES-1 and has a significant inhibitory effect on the acute inflammation model in vivo. | |||||||||||||||||||||
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Keywords