2305415-97-6
Chemical Structure
2’,3’-Bis(O-t-butyldimethylsilyl)-2-thiouridine
- CAS No.: 2305415-97-6
- Formula:C21H40N2O5SSi2
- Molecular Weight:488.79
IUPAC Name: 1-((2R,3R,4R,5R)-3,4-bis((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
InChIKey: OTRKFKREBPGFCB-VDHUWJSZSA-N
SMILES: O=C(C=CN1[C@H]2[C@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CO)O2)NC1=S
Biological Activity: 2’,3’-Bis(O-t-butyldimethylsilyl)-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’,3’-Bis(O-t-butyldimethylsilyl)-2-thiouridine | 2’,3’-Bis(O-t-butyldimethylsilyl)-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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