2306305-57-5
2306305-57-5
Chemical Structure
NEU-4438
- CAS No.: 2306305-57-5
- Formula:C24H26N8
- Molecular Weight:426.52
IUPAC Name: (E)-1-methyl-7-(2-(4-methyl-1,4-diazepan-1-yl)pyrimidin-5-yl)-N-(pyrazin-2-yl)quinolin-4(1H)-imine
InChIKey: LFNQOALWYMCTGA-XHLNEMQHSA-N
SMILES: CN1CCN(C2=NC=C(C3=CC(N(C)C=C/4)=C(C=C3)C4=N\C5=NC=CN=C5)C=N2)CCC1
Biological Activity: NEU-4438 is an antimalarial agent. NEU-4438 inhibits DNA synthesis, reduces AMPK-γ, and increases Clathrin heavy chain. NEU-4438 exhibits antiparasitic activity against Trypanosoma brucei. NEU-4438 reduces trypanosome tissue burden in a chronic HAT mouse model[1].
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NEU-4438 | NEU-4438 is an antimalarial agent. NEU-4438 inhibits DNA synthesis, reduces AMPK-γ, and increases Clathrin heavy chain. NEU-4438 exhibits antiparasitic activity against Trypanosoma brucei. NEU-4438 reduces trypanosome tissue burden in a chronic HAT mouse model. | |||||||||||||||||||||
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References
Keywords
