2307277-92-3
2307277-92-3
Chemical Structure
(R,R)-LRRK2-IN-7
- CAS No.: 2307277-92-3
- Formula:C24H26N6O
- Molecular Weight:414.50
InChIKey: JCQABEJXHUSDMF-KOSHJBKYSA-N
SMILES: CC(C)(O)[C@@H]1CCN(C1)C2=NC=NC(N3C4=CC([C@]5(CC56CC6)C#N)=CC=C4C=N3)=C2
Biological Activity: (R,R)-LRRK2-IN-7 is the isomer of LRRK2-IN-7 (HY-152107). LRRK2-IN-7 is a potent, selective, and CNS-penetrant LRRK2 kinase inhibitor with an IC50 of 0.9 nM. LRRK2-IN-7 shows >1000-fold selectivity over other kinases, ion channels, and CYP enzymes.
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(R,R)-LRRK2-IN-7 | (R,R)-LRRK2-IN-7 is the isomer of LRRK2-IN-7 (HY-152107). LRRK2-IN-7 is a potent, selective, and CNS-penetrant LRRK2 kinase inhibitor with an IC50 of 0.9 nM. LRRK2-IN-7 shows >1000-fold selectivity over other kinases, ion channels, and CYP enzymes. | |||||||||||||||||||||
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Keywords
