2341796-76-5
Chemical Structure
(S,R,S)-AHPC-PEG2-NH2 dihydrochloride
Synonym(s): VH032-PEG2-NH2 dihydrochloride
- CAS No.: 2341796-76-5
- Formula:C28H43Cl2N5O6S
- Molecular Weight:648.64
IUPAC Name: (2S,4R)-1-((S)-2-(2-(2-(2-aminoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
InChIKey: JHDIGXLPWYVAKX-OTCWRJAQSA-N
SMILES: O=C([C@H]1N(C([C@@H](NC(COCCOCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2.Cl.Cl
Biological Activity: (S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-PEG2-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs[1].
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(S,R,S)-AHPC-PEG2-NH2 dihydrochloride | (S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-PEG2-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs. | |||||||||||||||||||||
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