2359689-76-0
2359689-76-0
Chemical Structure
SOS1-IN-3
- CAS No.: 2359689-76-0
- Formula:C21H21F3N4O
- Molecular Weight:402.41
IUPAC Name: (R)-4-((1-(3-(difluoromethyl)-2-fluorophenyl)ethyl)amino)-2-methyl-6-(1-methylcyclopropyl)pyrido[4,3-d]pyrimidin-7(6H)-one
InChIKey: LJTJIUYTAZPUMG-LLVKDONJSA-N
SMILES: C[C@H](C1=C(C(C(F)F)=CC=C1)F)NC(C2=CN3C4(CC4)C)=NC(C)=NC2=CC3=O
Biological Activity: SOS1-IN-3 is a potent SOS1 (son of sevenless homolog 1) inhibitor with an IC50 of 5 nM. SOS1-IN-3 has anticancer effects (WO2019122129A1; compound I-1)[1].
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SOS1-IN-3 | SOS1-IN-3 is a potent SOS1 (son of sevenless homolog 1) inhibitor with an IC50 of 5 nM. SOS1-IN-3 has anticancer effects (WO2019122129A1; compound I-1). | |||||||||||||||||||||
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References
Keywords
