2375048-04-5
2375048-04-5
Chemical Structure
DDC4002
- CAS No.: 2375048-04-5
- Formula:C20H15FN2O
- Molecular Weight:318.35
IUPAC Name: 10-benzyl-8-fluoro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one
InChIKey: NKFCUHMOEKHJLB-UHFFFAOYSA-N
SMILES: O=C1C=2C=CC=CC2NC3=CC=C(F)C=C3N1CC=4C=CC=CC4
Biological Activity: DDC4002 is a selective EGFR inhibitor. DDC4002 has inhibitory activity against the L858R/T790M mutant EGFR subtype (IC50 = 39 nM)[1].
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DDC4002 | DDC4002 is a selective EGFR inhibitor. DDC4002 has inhibitory activity against the L858R/T790M mutant EGFR subtype (IC50 = 39 nM). | |||||||||||||||||||||
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References
Keywords
