2389064-43-9
Chemical Structure
DAPOA
- CAS No.: 2389064-43-9
- Formula:C5H8N6O3
- Molecular Weight:200.16
IUPAC Name: 2-((1,3-diazidopropan-2-yl)oxy)acetic acid
InChIKey: WDGRABVNFATWJY-UHFFFAOYSA-N
SMILES: [N-]=[N+]=NCC(CN=[N+]=[N-])OCC(O)=O
Biological Activity: DAPOA is a click chemistry reagent containing an azide group. DAPOA can be used in peptide synthesis as a linker that can be further modified at the azido-groups using Staudinger ligation or click-chemistry[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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DAPOA | DAPOA is a click chemistry reagent containing an azide group. DAPOA can be used in peptide synthesis as a linker that can be further modified at the azido-groups using Staudinger ligation or click-chemistry. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Keywords
