2389988-21-8
2389988-21-8
Chemical Structure
1-Amino-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine
- CAS No.: 2389988-21-8
- Formula:C10H14N6O6
- Molecular Weight:314.25
IUPAC Name: 1,2-diamino-9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7,9-dihydro-1H-purine-6,8-dione
InChIKey: SIXZCFPRAGPNFK-SAFLGMAISA-N
SMILES: O[C@@H]1[C@@H](O)[C@H](N(C(N2)=O)C3=C2C(N(N)C(N)=N3)=O)O[C@@H]1CO
Biological Activity: 1-Amino-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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1-Amino-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine | 1-Amino-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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