2407854-18-4
2407854-18-4
Chemical Structure
BMS-502
- CAS No.: 2407854-18-4
- Formula:C27H22F2N6O3
- Molecular Weight:516.50
InChIKey: XAHMIJCNFUSTMT-UHFFFAOYSA-N
SMILES: N#CC1=NC2=C(N(C)C(C([N+]([O-])=O)=C2N3CCN(C(C4=CC=C(F)C=C4)C5=CC=C(F)C=C5)CC3)=O)C=C1
Biological Activity: BMS-502 (Compound 22) is a potent dual inhibitor of diacylglycerol kinase (DGK) α and ζ with IC50 of 4.6 nM and 2.1 nM. BMS-502 enhanced T cell immune responses in mice. BMS-502 can be used in tumor immunity related research[1].
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BMS-502 | 99.31% | BMS-502 (Compound 22) is a potent dual inhibitor of diacylglycerol kinase (DGK) α and ζ with IC50 of 4.6 nM and 2.1 nM. BMS-502 enhanced T cell immune responses in mice. BMS-502 can be used in tumor immunity related research. | ||||||||||||||||||||
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References
Keywords
