2411398-95-1
2411398-95-1
Chemical Structure
NTPAN-MI
- CAS No.: 2411398-95-1
- Formula:C29H26N4O2
- Molecular Weight:462.54
IUPAC Name: 3,3-bis(4-(dimethylamino)phenyl)-2-(4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl)acrylonitrile
InChIKey: CGOIFUPZTOUIMX-UHFFFAOYSA-N
SMILES: N#C/C(C1=CC=C(N2C(C=CC2=O)=O)C=C1)=C(C3=CC=C(N(C)C)C=C3)\C4=CC=C(N(C)C)C=C4
Biological Activity: NTPAN-MI is a fluorescent probe (excitation wavelength: 405 nm). NTPAN-MI is selectively activated after labeling unfolded proteins with exposed thiols, thereby reporting the degree of protein homeostasis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NTPAN-MI | 96.87% | NTPAN-MI is a fluorescent probe (excitation wavelength: 405 nm). NTPAN-MI is selectively activated after labeling unfolded proteins with exposed thiols, thereby reporting the degree of protein homeostasis. | ||||||||||||||||||||
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References
- [1]. Owyong TC, et al. A Molecular Chameleon for Mapping Subcellular Polarity in an Unfolded Proteome Environment. Angew Chem Int Ed Engl. 2020 Jun 15;59(25):10129-10135. [Content Brief]
- [2]. Zhang S, et al. Measuring Cysteine Exposure in Unfolded Proteins with Tetraphenylethene Maleimide and its Analogs. Methods Mol Biol. 2022;2378:3-18. [Content Brief]
Keywords
